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Treatment is combined with diet and exercise. The medicine helps your body to use insulin better. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.</p> <h2>What should I tell my health care providers before I take this medicine?</h2> <p>They need to know if you have any of these conditions:</p> <ul> <li>diabetic ketoacidosis </li> <li>heart disease </li> <li>kidney disease </li> <li>liver disease </li> <li>severe infection or injury </li> <li>thyroid disease </li> <li>an unusual or allergic reaction to glyburide, sulfa drugs, other medicines, foods, dyes, or preservatives </li> <li>pregnant or trying to get pregnant </li> <li>breast-feeding</li> </ul> <h2>How should I use this medicine?</h2> <p>Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. If you take this medicine once a day, take it with breakfast or the first main meal of the day. Take your medicine at the same time each day. Do not take more often than directed.</p> <p>Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.</p> <p>Elderly patients over 65 years old may have a stronger reaction and need a smaller dose.</p> <p>Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.</p> <p>Note: This medicine is only for you. Do not share this medicine with others.</p> <h2>What if I miss a dose?</h2> <p>If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.</p> <h2>What may interact with this medicine?</h2> <ul> <li>bosentan </li> <li>chloramphenicol </li> <li>cisapride </li> <li>medicines for fungal or yeast infections </li> <li>metoclopramide </li> <li>probenecid </li> <li>warfarin </li> </ul> <p>Many medications may cause an increase or decrease in blood sugar, these include:</p> <ul> <li>alcohol containing beverages </li> <li>aspirin and aspirin-like drugs </li> <li>chloramphenicol </li> <li>chromium </li> <li>female hormones, like estrogens or progestins and birth control pills </li> <li>heart medicines </li> <li>isoniazid </li> <li>male hormones or anabolic steroids </li> <li>medicines for weight loss </li> <li>medicines for allergies, asthma, cold, or cough </li> <li>medicines for mental problems </li> <li>medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl </li> <li>niacin </li> <li>NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen </li> <li>pentamidine </li> <li>phenytoin </li> <li>probenecid </li> <li>quinolone antibiotics like ciprofloxacin, levofloxacin, ofloxacin </li> <li>some herbal dietary supplements </li> <li>steroid medicines like prednisone or cortisone </li> <li>thyroid medicine </li> <li>water pills or diuretics</li> </ul> <p>This list may not describe all possible interactions. 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